InterSystems
About
Healthcare data platform company powering some of the most complex clinical integration environments in the world — privately held, Cambridge, Massachusetts. InterSystems HealthShare provides enterprise health information exchange, FHIR platform, and clinical analytics. InterSystems IRIS for Health is the database and integration engine underlying Epic, many laboratory systems, and major HIEs globally. Caché (predecessor to IRIS) runs the Epic database — InterSystems is the hidden infrastructure...
Details
VenSearch Intelligence
Ideal Customer
- InterSystems skews strongly toward large enterprise and mission-critical environments; customer data indicates that 41% of its users are at organizations with over 1,000 employees, and marquee customers include Epic, LabCorp, Stanford Health Care, Mass General Brigham, Northwell Health, Providence St. Joseph Health, and large national/regional HIEs.
- Its IRIS platform powers Epic environments supporting 2.5 million concurrent users processing 1.8 billion database operations per second, illustrating its positioning at the high end of enterprise scale.
Key Differentiators
- InterSystems differentiates on extreme performance and reliability at scale — its IRIS platform processes roughly 1.8 billion database operations per second across Epic's customer base — and on a unified, multi-model architecture that combines transactional database, interoperability, analytics, and AI in a single engine, avoiding the need to stitch together disparate tools.
- The company received four Global 2026 Best in KLAS awards (TrakCare for Acute Care EHR in France, Asia, and Oceania; HealthShare for Shared Care Records in Europe for the third consecutive year) and is named in the 2025 and 2026 Gartner Magic Quadrant for Cloud Database Management Systems and Enterprise EHR respectively.
Industries Served
- InterSystems primarily serves healthcare and life sciences — including hospitals, health systems, payers, HIEs, clinical labs, and health IT software developers — but also serves financial services, supply chain and logistics, manufacturing, mining, retail/consumer goods, and government.
- The company recently launched InterSystems Public Sector Corporation (IPSC), a dedicated subsidiary for federal, state, and local government agencies.
Service Coverage
- InterSystems operates globally, with software deployed in over 80 countries and 38–39 office locations spanning 28 countries across the Americas, Europe, Africa, the Middle East, and Asia-Pacific.
- The company provides 24/7 support through its Worldwide Response Center in all of those markets.
Partnerships
- InterSystems holds advanced technology partner status with Amazon Web Services (AWS) and has formal cloud partnerships with Microsoft Azure, Google Cloud, Tencent, and Alibaba, with its platforms available through major cloud marketplaces.
- The company has a long-standing and deeply embedded relationship with Epic Systems — InterSystems IRIS is the database engine underlying Epic, and InterSystems has listed its Payer Connector product directly on the Epic Showroom.
Company Size & Ownership
- InterSystems was founded in 1978 by Phillip (Terry) Ragon and employs approximately 2,400 people worldwide as of 2024.
- The company crossed $1 billion in annual revenue in 2023 and reported revenues exceeding $1.1 billion in FY2024, reflecting sustained organic growth.
Compliance & Certifications
- InterSystems maintains a security program based on ISO 27001 (incorporating NIST SP 800-53) and requires its U.S. managed services operations to be audited for both SOC 2 Type 2 and HITRUST CSF Certification annually; UK managed services operations are audited for ISO 27001, ISO 22301, and ISO 20000-1.
- Its broader cybersecurity framework incorporates HIPAA, NIST, APEC CBPR, and EU GDPR requirements.
Compiled from public sources by VenSearch · Last researched October 14, 2026
Offerings
2 offeringsInterSystems HealthShare
Health information exchange and FHIR platform — enables patient data sharing across EHRs, payers, public health agencies, and care coordination platforms. HealthShare Personal Community provides patient-facing data access. Underpins many state and regional HIEs in the US. Used by CommonWell and Carequality network participants for cross-organizational data sharing.
InterSystems IRIS for Health
High-performance database and integration engine with native FHIR support — the successor to InterSystems Caché, which runs the Epic database. IRIS for Health provides HL7, FHIR, and API-based integration across clinical systems. Used by Epic, laboratory systems, and health information exchanges as the data management foundation.
Considering InterSystems?
Our team will work with you to determine if InterSystems is the right fit for your organization. From research and assessment through procurement negotiation and ongoing vendor management — we handle the entire process at no cost to you.